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18 juillet 2012

TNF alpha's structure

TNF is primarily produced as a 212-amino acid-long type II transmembrane protein arranged in stable homotrimers. From this membrane-integrated form the soluble homotrimeric cytokine (sTNF) is released via proteolytic cleavage by the metalloprotease TNF...

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11 octobre 2012

chemical synthesis

A total synthesis is the complete chemical synthesis of complex organic molecules from simple, commercially available (petrochemical) or natural precursors. In a linear synthesis—often adequate for simple structures—several steps are performed one after...

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16 octobre 2012

TNF alpha

Tumor necrosis factor (TNF, cachexin, or cachexia quality, previously known as tumor necrosis factor-alpha, or TNF-α), a cytokine involved in systemic inflammatory response, and is a part of a group of cytokines stimulate the acute phasereaction. It mainly...

Posté par lliu11776 à 17:07 - Commentaires […] - Permalien [#]

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26 octobre 2012

total synthesis

A total synthesis of the complete chemical synthesis of complex organic molecules from simple, commercially available (petrochemical) or natural precursors. In a linear synthesis is usually sufficient, a simple structure, in several steps one after another,...

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4 novembre 2012

Transforming growth factor beta 1

Transforming growth factor beta 1 and transforming growth factor - β 1 peptides of the transforming growth factor β cytokine family . It is a secreted protein , execution of many cellular functions , including the control of cell growth , cell proliferation...

Posté par lliu11776 à 15:34 - Commentaires […] - Permalien [#]

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18 juillet 2012

What is tnf alpha?

Tumor necrosis factor (TNF, cachexin, or cachectin, and formerly known as tumor necrosis factor-alpha orTNF-α) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate theacute phase reaction. It is produced...

Posté par lliu11776 à 13:11 - Commentaires […] - Permalien [#]

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15 novembre 2012

FGF10 Acts as a Major Ligand for FGF Receptor 2 IIIb in Mouse Multi-Organ Development

Fibroblast growth factor receptor 2 subtype stage IIIB (FGFR2b) receptor initially found FGF7, is known to be important in vertebrate morphology receptor FGFR2b knockout mice showed developmental or developmentalinsufficiency of various organs, budding...

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20 novembre 2012

A long-acting FSH agonist through fusing human chorionic gonadotropin beta subunits of the FSHβ

Follicle stimulating hormone (FSH) is a pituitary glycoprotein hormones, ovarian follicles and seminiferous tubules of the testis development is essential. FSH is used clinically to stimulate follicular maturation, in vitro fertilization and the treatment...

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27 novembre 2012

Recent advances in olefin metathesis and its application in organicsynthesis

The latest progress in olefin metathesis reaction, the key areas of ring-closing olefin metathesis reaction (RCM) and cross-metathesis review. Numerous display olefin metathesis reaction, the catalytic activity of the complexes, the definition of the...

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27 novembre 2012

catalytic methods for organic synthesis

This much needed resource brings together a wealth of procedures for the synthesis and practical use of diazocarbonyl compounds. It features methods for the preparation of important catalysts and for applications of diazocarbonyl compounds within each...

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27 novembre 2012

Supramolecular Synthons in Crystal Engineering—A New Organic Synthesis

Crystals of organic compounds, the final supramolecular and solid state molecular recognition and its assembly, chemical and geometric factors, from a single molecule is the best example. The description of the crystal structure of the implicit supramolecular...

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6 décembre 2012

Use of Recombinant Human Bone Morphogenetic Protein-2 to Enhance Tendon Healing in a Bone Tunnel

The assumptions of the study, recombinant human bone morphogenetic protein-2 into the bone tunnel placed a tendon enhances bone ingrowth. Long digital extensor tendon transplant to the drilling of the proximal tibia of 65 adult mongrel dogs. Use of one...

Posté par lliu11776 à 16:21 - Commentaires […] - Permalien [#]

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6 décembre 2012

Recombinant human bone morphogenetic protein-2 and collagen for bone regeneration

The report describes a recombinant human bone morphogenetic protein-2 (rh BMP-2 ) in combination, and regeneration of bone collagen (C). Unilateral critical size defects (CSDS) in a radius of 32 bones mature New Zealand White rabbits. Rabbits were evenly...

Posté par lliu11776 à 16:22 - Commentaires […] - Permalien [#]

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18 juillet 2012

physiology of tnf alpha

TNF was thought to be produced primarily by macrophages, but it is produced also by a broad variety of cell types including lymphoid cells, mast cells, endothelial cells, cardiac myocytes, adipose tissue, fibroblasts, and neuronal tissue. Large amounts...

Posté par lliu11776 à 13:19 - Commentaires […] - Permalien [#]

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17 octobre 2012

Guanine nucleotide exchange structure foundation run regulator ChromosomeCondensation (RCC1)

RCC1 (regulator chromosomecondensation), beta propeller chromatin-binding protein, guanine nucleotide exchange factor (GEF) for the nuclear GTP-binding protein contingent. Here, we report the 1.8 angstrom crystal structure Ran • RCC1 complex nucleotide...

Posté par lliu11776 à 18:17 - Commentaires […] - Permalien [#]

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26 octobre 2012

Organic synthesis

Organic synthesis is a special branch of chemical synthesis and concerns the construction of organic compounds through organic reactions. Organic molecules compared to pure inorganic compound, can often contain a higher level of complexity, it has been...

Posté par lliu11776 à 15:59 - Commentaires […] - Permalien [#]

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4 novembre 2012

tgfb1 function

TGFB is a multifunctional peptide , control of proliferation , differentiation , and other functions in many types of cells . TGFB acts synergistically with triglyceride fatty acid induced transformation . It also acts as a negative autocrine growth factor...

Posté par lliu11776 à 15:35 - Commentaires […] - Permalien [#]

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12 novembre 2012

Clusterin

Clusterin (apolipoprotein J) is a 75 - 80 kDa disulfide-linked dimeric protein and cell debris and apoptosis of different gap. In humans, clusterin the CLU gene encoding. This protein has several synonyms: dimer acid glycoprotein (DAG protein), testosterone...

Posté par lliu11776 à 15:14 - Commentaires […] - Permalien [#]

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12 novembre 2012

Clusterin inhibits apoptosis by interacting with activated Bax

Clusterin is a mysterious glycoprotein overexpressed in a variety of human cancers, such as prostate cancer and breast cancer, as well as squamous cell carcinoma1, 2. Since the inhibit clusterin expression presents a sensitive human tumor cells to chemotherapeutic...

Posté par lliu11776 à 15:15 - Commentaires […] - Permalien [#]

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28 septembre 2012

CSK c-src tyrosine kinase

Tyrosine kinase CSK mouse embryonic development is essential. The CSK gene knock the dead mice in the early stages of embryonic development embryonic day 10 (approximately). The molecular mechanism of this defect is not completely understood. Here, we...

Posté par lliu11776 à 14:53 - Commentaires […] - Permalien [#]

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23 août 2012

Organic synthesis

Organic synthesis is a special branch of chemical synthesis and is concerned with the construction of organic compounds via organic reactions. Organic molecules can often contain a higher level of complexity compared to purely inorganic compounds, so...

Posté par lliu11776 à 16:15 - Commentaires […] - Permalien [#]

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29 août 2012

total synthesis

A total synthesis is the complete chemical synthesis of complex organic molecules from simple, commercially available (petrochemical) or natural precursors. In a linear synthesis—often adequate for simple structures—several steps are performed one after...

Posté par lliu11776 à 16:52 - Commentaires […] - Permalien [#]

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4 septembre 2012

Organic Synthesis-A publication of reliable methods for the preparation of organic copounds

Since 1921, Organic Syntheses has provided the chemistry community with detailed, reliable, and carefully checked procedures for the synthesis of organic compounds. Some procedures describe practical methods for the preparation of specific compounds of...

Posté par lliu11776 à 14:56 - Commentaires […] - Permalien [#]

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16 septembre 2012

Il10 interleukin 10

nterleukin -10 (IL-10) inhibition of antigen-presenting cells (APC) T_ ( H1 ) ( 1 type helper T cells ) produce cytokines may directly promote the proliferation of T cells and mast cell lines . IL-10 is on lymphocytes , bone marrow cells having a diversity...

Posté par lliu11776 à 15:48 - Commentaires […] - Permalien [#]

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22 septembre 2012

MVD mevalonate (diphospho) decarboxylase in the structural and functional characteristics of the simulation.

Mevalonate-5 - phosphate decarboxylase (MVD) is an important enzyme in the mevalonate pathway in the catalytic ATP-dependent the mevalonate -5 - phosphate (MDP), obtained isoprene phosphorylation (IPP), which is a ubiquitous isoprenoid and sterol precursor...

Posté par lliu11776 à 15:20 - Commentaires […] - Permalien [#]

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