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16 octobre 2012

Tumor necrosis factors

Tumor necrosis factor (TNF family) refers to a group of cytokines, its family can cause cell death (apoptosis). The first two family members to determine:Tumor necrosis factor (TNF), formerly known as TNF-α, and this class is the most famous members....

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16 octobre 2012

Cloning and expression of a human tumor necrosis factor receptor gene.

A human tumor necrosis factor (TNF) from the serum of cancer patients in the binding protein was purified to homogeneity and partial sequencing. TNF receptor used to isolate cDNA clones encoding the amino acid sequence information on the basis of the...

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17 octobre 2012

RCC1 protein, the incidence of chromosome condensation is positioned within the nucleus regulator

RCC1 gene, a regulator for chromosome condensation was found that the protein encoded in the pathogenesis, its molecular weight is 45 kD, the preparation of synthetic peptides based on the amino acid sequence of the assumed RCC1 using the antibody determination....

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17 octobre 2012

The 1.7 Å crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-blade

By virtue of its ability to complement hamster cell line tsBN2, it has undergone premature chromosome condensation or cell cycle arrest in G1 phase of the non-temperature-sensitive phenotype cloned genes encoded in chromosome condensation ( RCC1 ) the...

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26 octobre 2012

Stereoselective synthesis

The most complex natural products is chiral, different biological activity of the enantiomer of the chiral molecules. The traditional full synthesis of the targeted racemic mixture, i.e., the two as an equal mixture of enantiomers possible. By chiral...

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30 octobre 2012

MSX1-mediated epidermal induction and neural inhibition of BMP4

Has been proved by the secretion of growth factors, bone morphogenetic protein 4 (BMP4) induced epidermal fate in Xenopus ectoderm. However, little is known about the molecular mechanism of this reaction. Here, we show that the expression of homeobox...

Posté par lliu11776 à 16:24 - Commentaires […] - Permalien [#]

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30 octobre 2012

Bone morphogenetic protein 4 (BMP4): A regulator of capsule chondrogenesis in the dev

Formed cartilage ear capsules for by the the ear epithelium ear weekday mesenchymal interactions. Reaction induced ear epithelial cells, mesenchymal aggregation appears the periphery region of the ear, and the formation of a chondrified ear capsule, as...

Posté par lliu11776 à 16:25 - Commentaires […] - Permalien [#]

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30 octobre 2012

Rhombencephalic neural crest of the signaling molecule BMP4-mediated apoptosis.

Pattern in the head region of the gill skeleton structure and muscle by neural crest1, its cells appear hindbrain the discrete segmental level chicks: specifically, Ling (R) L +2, r4 and r6 profound impact, andthe r3 and R5 crest depleted2. We have demonstrated...

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4 novembre 2012

TGF-β1 and T cells

Some T cells (regulatory T cells) release of TGF-β1 inhibition of the action of other T cells. Interleukin 1 - and interleukin-2-dependent proliferation of activated T cells, and static helper T cells and cytotoxic T cell activation, and to prevent by...

Posté par lliu11776 à 15:34 - Commentaires […] - Permalien [#]

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8 novembre 2012

Supramolecular Synthons in Crystal Engineering—A New Organic Synthesis

Crystal of organic compounds is the ultimate supramolecular , and their combination , by chemical and geometrical factors , from the single molecule is a perfect example of solid , molecular recognition . Implicit in the supramolecular describing crystal...

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8 novembre 2012

Endogenous production, delivery and effects of exogenous shock synthesis of organic molecules

The sources of organic molecules on the early Earth is divided into three categories: delivery by extraterrestrial objects; organic synthesis effect of impact driving; and organic synthesis of other energy sources ( such as ultraviolet or discharge )....

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8 novembre 2012

Atom Economy—A Challenge for Organic Synthesis: Homogeneous Catalysis Leads the Way

To improve the efficiency of the synthesis of complex organic product consists of synthetic chemists of the most exciting challenge. Add directory reaction, is the simple increase or reduce waste generation is a necessary first step. Transition metal...

Posté par lliu11776 à 14:22 - Commentaires […] - Permalien [#]

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12 novembre 2012

Molecular biology of Clusterin

The protein itself is a disulfide-linked heterodimeric protein, rich in sialic acid containing about 30% of N-linked carbohydrate. Truncated forms of targeting to the nucleus have been identified. Polypeptide chain precursor by proteolytic cleavage to...

Posté par lliu11776 à 15:16 - Commentaires […] - Permalien [#]

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15 novembre 2012

FGF10 and branching morphogenesis in the embryonic mouse lung

Growth and branching in mouse lung tissue morphology, remote adjustment adjacent mesenchymal endoderm. We report here, said dynamic buds at the end of the the adjacent interstitial lung development in the early stages of the fibroblast growth factor 10...

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15 novembre 2012

Fibroblast growth factor 10

Fibroblast growth factor 10, in the human FGF10 gene encodes a protein. The proteins encoded by this gene is a fibroblast growth factor (FGF) family. Fibroblast growth factor family members with a wide range of mitosis and cell survival activities, and...

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20 novembre 2012

Site specific mutations in the intracellular roles of asparagine-linked oligosaccharides

The β subunit of human chorionic gonadotropin containing asparagine ( ) - linked oligosaccharides . A review of the structure and function , these oligosaccharide unit in vivo , we constructed mutants containing genes change or asparagine or threonine...

Posté par lliu11776 à 15:15 - Commentaires […] - Permalien [#]

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20 novembre 2012

Detection and characterization of the placenta small RNA in maternal plasma

Background: circulating maternal plasma fetal nucleic acid discovery opens up new possibilities for noninvasive prenatal diagnosis. Small molecule RNA (miRNAs) are a class of small RNA, a recent in-depth investigation, because of their important role...

Posté par lliu11776 à 15:15 - Commentaires […] - Permalien [#]

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6 décembre 2012

Use of Bone Morphogenetic Protein-2 in the Rabbit Ulnar Nonunion Model

Protein and recombinant human bone morphogenetic protein-2 with polyglycolic acid porous microspheres and autologous blood clots combination to treat large defect in rabbit femoral shaft defect model of bone induction test. Two kinds to cm nonuniting...

Posté par lliu11776 à 16:22 - Commentaires […] - Permalien [#]

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